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Thiamin supplements may also help for people who experience: malabsorption syndrome severe, prolonged vomiting gastric bypass surgery renal replacement therapy hyperthyroidism People who are pregnant, lactating, or use diuretics may also benefit from vitamin B1 supplements

these were not completed in peer-reviewed form, and a Phase I safety study has been mentioned in the literature but its results were never published

In other embodiments, the enhanced viscosity formulation or composition includes a pharmaceutically acceptable buffer